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Decant arbitrage. Potions of the same type but different dose sizes often trade at different prices per dose. Because decanting is lossless (three 4-dose = four 3-dose), you can buy the cheapest-per-dose size, decant, and sell the richest — pure profit on the gap, after the 2% sell tax. Decant for free at Zahur (Nardah) or Bob Barter (Grand Exchange, members), 5 gp per extra vial when splitting down. Profit is per potion you sell; it's capped by buy limits and your decanting time, and prices are live so margins move. See the decanting guide. Not affiliated with Jagex; not financial advice.
All · F2P
#PotionBuy (dose)→ Sell (dose) Profit / potion/ dose24h vol
1Prayer regeneration potion(3) @ 50.4k(4) @ 74.7k+6.1k15282,483
2Bastion potion(3) @ 10.9k(4) @ 16.5k+1.6k4032,447
3Super combat potion(3) @ 9.2k(1) @ 3.5k+3463461,192
4Antidote++(3) @ 4.6k(4) @ 7.4k+1.1k2851,166
5Divine ranging potion(4) @ 7.2k(1) @ 2.0k+1341355,049
6Stamina potion(1) @ 900(3) @ 3.1k+3441155,237
7Saradomin brew(1) @ 1.8k(4) @ 7.9k+4471122,534
8Ranging potion(2) @ 1.0k(1) @ 640+1041051,512
9Armadyl brew(4) @ 1.4k(3) @ 1.3k+243813,358
10Super energy(3) @ 1.8k(4) @ 2.7k+2736851,442
11Prayer potion(1) @ 2.1k(4) @ 8.6k+169421,478
12Super restore(3) @ 8.2k(4) @ 11.3k+1393548,606
13Super defence(3) @ 2.9k(4) @ 4.1k+1132845,989
14Super attack(3) @ 1.6k(4) @ 2.3k+942452,276
15Super strength(3) @ 2.4k(4) @ 3.4k+431172,736
16Antifire potion(3) @ 710(4) @ 993+26710,898
17Energy potion F2P(4) @ 190(3) @ 166+18611,464